Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30853312 | 0.90 | PARP1 (0.31) | — | |
| SCHEMBL29168359 | 0.90 | AXL (0.31) | KDM4E | |
| SCHEMBL27186283 | 0.80 | PRKAB2 (0.35) | PKMKDM4E | |
| SCHEMBL29168393 | 0.72 | KRAS (0.33) | — | |
| SCHEMBL29168391 | 0.72 | KRAS (0.33) | — | |
| SCHEMBL27186991 | 0.72 | HSD17B10 (0.50) | KDM4E | |
| SCHEMBL27186177 | 0.70 | PDK2 (0.36) | KDM4E | |
| SCHEMBL27186394 | 0.67 | ALDH1A1 (0.36) | KDM4E | |
| SCHEMBL27186153 | 0.65 | ECE1 (0.40) | KDM4E | |
| SCHEMBL30853366 | 0.64 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |