Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168454 | 0.90 | PKM (0.31) | — | |
| SCHEMBL29168359 | 0.89 | AXL (0.31) | — | |
| SCHEMBL30853331 | 0.71 | JAK2 (0.39) | — | |
| SCHEMBL27186283 | 0.70 | PRKAB2 (0.35) | IRAK4 | |
| SCHEMBL27186177 | 0.69 | PDK2 (0.36) | IRAK4 | |
| SCHEMBL30853309 | 0.68 | ALDH1A1 (0.34) | PARP1 | |
| SCHEMBL30853313 | 0.67 | — | — | |
| SCHEMBL18670649 | 0.66 | PARP1 (0.37) | PARP1 | |
| SCHEMBL30853390 | 0.66 | EGFR (0.37) | PARP1 | |
| SCHEMBL30853351 | 0.63 | PARP1 (0.43) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |