Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177259 | 0.88 | GPR35 (0.43) | KMT2AKDM4EHSD17B10MEN1ALDH1A1 | |
| SCHEMBL17238588 | 0.82 | ENPP2 (0.42) | KMT2AMEN1THRBTHRASMN1; SMN2 | |
| SCHEMBL29739422 | 0.81 | POLB (0.55) | KMT2AKDM4EMEN1ALDH1A1THRB | |
| SCHEMBL19778549 | 0.77 | LMNA (0.47) | KMT2AKDM4EMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL26087466 | 0.77 | THRA (0.42) | KMT2AKDM4EALDH1A1THRBTHRA | |
| SCHEMBL29177360 | 0.72 | MEN1 (0.41) | KMT2AKDM4EMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23973914 | 0.72 | ALDH1A1 (0.45) | KMT2AKDM4EHSD17B10MEN1ALDH1A1 | |
| SCHEMBL2097418 | 0.72 | THRA (0.44) | KMT2AKDM4EHSD17B10MEN1ALDH1A1 | |
| SCHEMBL10870818 | 0.71 | KMT2A (0.52) | KMT2AMEN1ALDH1A1THRBTHRA | |
| SCHEMBL16722682 | 0.71 | IDO1 (0.60) | KMT2AKDM4EMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |