Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RORC | P51449 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12144990 | 0.85 | RORC (0.40) | LMNAALDH1A1RORCSMN1; SMN2EGLN2 | |
| SCHEMBL12144653 | 0.85 | KDR (0.43) | ALDH1A1RORCKMT2AGAATDP1 | |
| SCHEMBL20535682 | 0.78 | LMNA (0.56) | LMNAALDH1A1RORCSMN1; SMN2KMT2A | |
| SCHEMBL16728601 | 0.77 | ALDH1A1 (0.63) | LMNAALDH1A1RORCSMN1; SMN2GAA | |
| SCHEMBL29177276 | 0.77 | KMT2A (0.39) | LMNAALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL6566913 | 0.76 | LMNA (0.59) | LMNAALDH1A1RORCSMN1; SMN2KMT2A | |
| SCHEMBL12332367 | 0.76 | LMNA (0.54) | LMNAALDH1A1RORCSMN1; SMN2KMT2A | |
| SCHEMBL1675548 | 0.75 | RORC (0.47) | ALDH1A1RORCSMN1; SMN2EGLN2IDO1 | |
| SCHEMBL13602356 | 0.75 | LMNA (0.52) | LMNAALDH1A1RORCSMN1; SMN2KMT2A | |
| SCHEMBL5009128 | 0.75 | GPR35 (0.63) | LMNAALDH1A1SMN1; SMN2EGLN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563120-B | alpha-D-galactoside inhibitors of galectins | 格莱克特生物技术公司 | 2022-12-02 | — | — | CN | disclosed |
| US-10988502-B2 | Alpha-D-galactoside inhibitors of galectins | GALECTO BIOTECH AB (DK) | 2021-04-27 | — | — | US | disclosed |
| US-10988502-B2 | Alpha-D-galactoside inhibitors of galectins | GALECTO BIOTECH AB (DK) | 2021-04-27 | — | — | US | disclosed |
| US-20190225638-A1 | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | GALECTO BIOTECH AB (DK) | 2019-07-25 | — | — | US | disclosed |
| US-20190225638-A1 | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | GALECTO BIOTECH AB (DK) | 2019-07-25 | — | — | US | disclosed |
| EP-3484903-A1 | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | Galecto Biotech AB (DK) | 2019-05-22 | — | — | EP | disclosed |
| WO-2018011093-A1 | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | GALECTO BIOTECH AB (DK) | 2018-01-18 | — | — | WO | disclosed |
| WO-2018011093-A1 | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | GALECTO BIOTECH AB (DK) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225638-A1 | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | LGALS1, LGALS2, LGALS3 | LMNA 470/4885ALDH1A1 561/4885RORC 2815/4885 |
| US-10988502-B2 | Alpha-D-galactoside inhibitors of galectins | LGALS1, LGALS2, LGALS3 | LMNA 470/4885ALDH1A1 561/4885RORC 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.