Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP4 | Q13107 | 1/20 | 0.61 |
| ▸ | USP7 | Q93009 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29191078 | 0.87 | EPHX2 (0.51) | USP4USP7EPHX2TP53HDAC1 | |
| SCHEMBL29191032 | 0.74 | AKR1C3 (0.65) | EPHX2HDAC1KDM1AMMP2MMP3 | |
| SCHEMBL5315293 | 0.72 | LOXL2 (0.60) | EPHX2HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL8483573 | 0.72 | ERCC1 (0.59) | USP4USP7TP53HDAC1HDAC3 | |
| SCHEMBL27306270 | 0.71 | USP4 (0.72) | USP4USP7HDAC1HDAC3HDAC4 | |
| SCHEMBL8373038 | 0.71 | EPHX2 (0.74) | EPHX2TP53HDAC1HDAC3HDAC6 | |
| SCHEMBL12993900 | 0.71 | EPHX2 (0.74) | EPHX2TP53HDAC1KDM1AMMP2 | |
| SCHEMBL28947613 | 0.71 | EPHX2 (0.74) | EPHX2TP53HDAC1KDM1AMMP2 | |
| SCHEMBL29951484 | 0.70 | PKM (0.47) | USP4USP7HDAC8 | |
| SCHEMBL20764583 | 0.69 | EPHX2 (0.72) | EPHX2HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886734-A | Heterocyclic amide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-16 | — | — | CN | disclosed |