Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | USP4 | Q13107 | 1/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | HRAS | P01112 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954724 | 0.92 | FABP4 (0.48) | PKMUSP4USP7KDM4EPOLB | |
| SCHEMBL12238277 | 0.77 | PKM (0.41) | PKMUSP4USP7ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL2364629 | 0.76 | PKM (0.40) | PKMUSP4USP7KDM4EPOLB | |
| SCHEMBL29950706 | 0.74 | ITGB3 (0.38) | PKMUSP4USP7KDM4EMAPT | |
| SCHEMBL2361283 | 0.73 | CYP2C9 (0.51) | PKMKDM4EPOLBHDAC8 | |
| SCHEMBL29953585 | 0.73 | ALDH1A1 (0.38) | KDM4EHDAC8LMNAL3MBTL1 | |
| SCHEMBL2644934 | 0.73 | CA1 (0.61) | POLBCA1CA2NPC1RAB9A | |
| SCHEMBL6499316 | 0.72 | HRAS (0.77) | PKMTOP1HRASESR1ESR2 | |
| Hydrochloric Acid SCHEMBL6497712 | 0.72 | KDM4E (0.59) | TOP1HRASESR1ESR2KDM4E | |
| SCHEMBL13117928 | 0.72 | TOP1 (0.57) | TOP1HRASESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |