Biphenyl

Biphenyl

SCHEMBL29199166

c1ccc(-c2ccccc2)cc1.c1ccc(C(=C(c2ccccc2)c2ccccc2-c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.52
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CHRNB2 P17787 2/20 0.46
CHRNB4 P30926 2/20 0.46
CHRNA3 P32297 2/20 0.46
CHRNA4 P43681 2/20 0.46
ALDH1A1 P00352 5/20 0.44
HPGD P15428 1/20 0.44
BCL2L1 Q07817 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HNF4A P41235 1/20 0.44
TSHR P16473 1/20 0.43
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
BACE1 P56817 1/20 0.41
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5572153 0.98 BCAT2 (0.54) BCAT2MEN1KMT2ASMN1; SMN2CHRNB2
Fluoride SCHEMBL29086928 0.93 BCAT2 (0.50) BCAT2MEN1KMT2ASMN1; SMN2CHRNB2
SCHEMBL22115687 0.85 AKR1C3 (0.41) BCAT2MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL28443188 0.84 SLC6A3 (0.51) BCAT2MEN1KMT2ASMN1; SMN2CHRNB2
SCHEMBL4071673 0.84 HNF4A (0.47) BCAT2MEN1KMT2ASMN1; SMN2CHRNB2
SCHEMBL28409211 0.84 ALDH1A1 (0.50) BCAT2MEN1KMT2ASMN1; SMN2CHRNB2
SCHEMBL6853035 0.84 HNF4A (0.43) BCAT2MEN1KMT2ASMN1; SMN2CHRNB2
SCHEMBL28442127 0.84 SLC6A4 (0.53) BCAT2MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL30377373 0.82 GAA (0.56) KMT2ASMN1; SMN2ALDH1A1HPGDHSD17B10
SCHEMBL9998265 0.81 BCAT2 (0.47) BCAT2MEN1KMT2ASMN1; SMN2CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957313-B Siloxane-bridged tetraphenyl ethylene derivatives, process for their preparation and their use 山东大学 2024-04-30 CN disclosed