SCHEMBL6853035

SCHEMBL6853035

c1ccc(C(=C(c2ccccc2)c2cccc(-c3ccccc3)c2C(=C(c2ccccc2)c2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.43
BCAT2 O15382 1/20 0.41
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 2/20 0.39
HPGD P15428 1/20 0.39
BCL2L1 Q07817 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
FOLH1 Q04609 1/20 0.37
MMP9 P14780 1/20 0.36
FABP3 P05413 1/20 0.36
FABP4 P15090 1/20 0.36
FABP5 Q01469 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5572153 0.86 BCAT2 (0.54) HNF4ABCAT2ALDH1A1HSD17B10HPGD
Biphenyl SCHEMBL29199166 0.84 BCAT2 (0.52) HNF4ABCAT2ALDH1A1HSD17B10HPGD
Fluoride SCHEMBL29086928 0.82 BCAT2 (0.50) HNF4ABCAT2ALDH1A1HSD17B10HPGD
SCHEMBL4071673 0.81 HNF4A (0.47) HNF4ABCAT2ALDH1A1HSD17B10HPGD
SCHEMBL28766699 0.80 HNF4A (0.37) HNF4ABCAT2ALDH1A1HSD17B10HPGD
SCHEMBL22115687 0.79 AKR1C3 (0.41) BCAT2ALDH1A1HSD17B10HPGDMEN1
SCHEMBL28443188 0.73 SLC6A3 (0.51) BCAT2ALDH1A1HPGDMEN1KMT2A
SCHEMBL28409211 0.73 ALDH1A1 (0.50) BCAT2ALDH1A1HSD17B10HPGDMEN1
SCHEMBL28442127 0.73 SLC6A4 (0.53) BCAT2HSD17B10HPGDMEN1KMT2A
SCHEMBL301948 0.73 ALDH1A1 (0.58) HNF4ABCAT2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3668718-A1 TAMPER-EVIDENT MATERIALS, ADHESIVES, SEALS, AND CONTAINERS Sun Chemical Corporation (US) 2020-06-24 EP disclosed
CN-102858911-B Tetraphenylethylene luminescent derivative, preparation method thereof and luminescent device using same UNIV HONG KONG SCIENCE & TECHN 2014-12-17 CN disclosed
US-6781148-B2 APPLYING POLYSILAZANE TO A SUBSTRATE AND; SUBJECTING THE APPLIED POLYSILAZANE TO OXIDATIVE TREATMENT, TO FORM A SILICA FILM OR SILICEOUS FILM ON SAID SUBSTRATE TDK CORPORATION (JP) 2004-08-24 US disclosed
US-6590554-B1 Color image display system TDK CORPORATION (JP) 2003-07-08 US disclosed
US-6501014-B1 PROTECTIVE SILICA COATING BY APPLYING A POLYSILAZANE SOLUTION TO A RESINOUS SUBSTRATE HAVING LIGHT TRANSPARENCY AND HEAT RESISTANCE, FOLLOWED BY STEAM OXIDATION AND HEAT TREATMENT; WEATHERPROOFING FOR OUTDOOR USE TDK CORPORATION (JP) 2002-12-31 US disclosed
US-20020113241-A1 Light emitting device TDK CORPORATION (JP) 2002-08-22 US disclosed
EP-1079668-A2 El display apparatus TDK Corporation (JP) 2001-02-28 EP disclosed