Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855783 | 0.82 | LMNA (0.37) | LMNAKMT2AMAPKAPK2MTNR1AMTNR1B | |
| SCHEMBL29223295 | 0.81 | MAPKAPK2 (0.34) | MAPTMAPKAPK2MTNR1AMTNR1BSTK17B | |
| SCHEMBL3742052 | 0.79 | RAB9A (0.44) | LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL2212160 | 0.76 | ACACB (0.41) | KMT2AALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL23703918 | 0.75 | MTNR1A (0.44) | LMNAKMT2AMTNR1AMTNR1B | |
| SCHEMBL7110934 | 0.74 | NLRP3 (0.40) | KMT2AMAPTMAPKAPK2LCK | |
| SCHEMBL29686979 | 0.74 | AKR1B1 (0.44) | LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL19975190 | 0.74 | AKR1B1 (0.44) | LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL1999697 | 0.73 | GABRA1 (0.38) | LMNAKMT2AMTNR1AMTNR1B | |
| SCHEMBL18512272 | 0.73 | STING1 (0.41) | LMNAKMT2AALDH1A1MAPKAPK2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507332-A | Octahydroisoquinolinyl derivatives | UCB生物制药有限责任公司 | 2023-07-28 | — | — | CN | disclosed |