SCHEMBL29237408

SCHEMBL29237408

C[Si](C)(C)OC(C#N)c1cccc(I)c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSB P07858 1/20 0.31
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30967873 1.00 CTSB (0.31) CTSBSLC6A3
SCHEMBL7088040 0.82 GAA (0.44)
SCHEMBL25831756 0.81 GAA (0.39)
SCHEMBL11038956 0.81 IDO1 (0.38)
SCHEMBL3830094 0.81 GAA (0.39)
SCHEMBL2610137 0.79 L3MBTL1 (0.42)
SCHEMBL3295316 0.79 TRPA1 (0.42)
SCHEMBL2610138 0.79 TRPA1 (0.42)
SCHEMBL9304481 0.77 ALDH1A1 (0.47)
SCHEMBL11039690 0.77 PNMT (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201919-A Indole compounds and methods of use 健赞公司 2024-06-14 CN disclosed