Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 3/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 6/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239988 | 1.00 | PTPN7 (0.40) | PTPN7DUSP3PNMTADRB1ADRA2A | |
| SCHEMBL16660435 | 0.86 | KIF11 (0.42) | PNMTFAAHPDE2ATRPV1 | |
| SCHEMBL16464213 | 0.83 | PNMT (0.54) | PNMTADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL8130819 | 0.80 | CES2 (0.46) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL18704180 | 0.79 | FAAH (0.38) | PTPN7DUSP3PNMTADRB1ADRA2A | |
| SCHEMBL27821733 | 0.79 | AKR1C3 (0.44) | SCN8AAKT1AKR1B10AKR1C4AKR1C3 | |
| SCHEMBL13710897 | 0.77 | SCN8A (0.36) | PTPN7DUSP3SCN8AAKR1C3AKR1C2 | |
| SCHEMBL3309320 | 0.77 | RXRA (0.43) | PDE2ASCN8ARXRAGRIN1GRIN2B | |
| SCHEMBL31085127 | 0.77 | RXRA (0.43) | PDE2ASCN8ARXRAGRIN1GRIN2B | |
| SCHEMBL8576357 | 0.76 | ADORA2A (0.41) | FAAHAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255686-A | Fluorine-containing trans-phenyl cyclopropylamine derivative, and preparation method and application thereof | 郑州大学 | 2024-06-28 | — | — | CN | disclosed |