SCHEMBL29248774

SCHEMBL29248774

NN1C(=O)C(c2ccccc2)=C(c2ccccc2)C1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.48
KMT2A Q03164 3/20 0.45
LCK P06239 1/20 0.42
PDE4B Q07343 1/20 0.41
NR1H2 P55055 2/20 0.41
NR1H3 Q13133 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
HTT P42858 1/20 0.40
FGFR1 P11362 1/20 0.38
SRC P12931 1/20 0.38
FGFR2 P21802 1/20 0.38
FGFR4 P22455 1/20 0.38
FGFR3 P22607 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
GAA P10253 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27316000 0.85 PTGS2 (0.42) PTGS2KMT2APDE4BNR1H2NR1H3
SCHEMBL794276 0.75 PTGS2 (0.69) PTGS2LCKPDE4BNR1H2NR1H3
SCHEMBL19577286 0.75 PTGS2 (0.44) PTGS2KMT2ALCKPDE4BNR1H2
SCHEMBL3876865 0.75 PTGS2 (0.44) PTGS2KMT2ALCKPDE4BNR1H2
SCHEMBL14777408 0.73 NR1H2 (0.53) PTGS2KMT2ANR1H2NR1H3HTT
SCHEMBL6310937 0.73 LCK (0.57) PTGS2LCKPDE4BNR1H2NR1H3
SCHEMBL29644690 0.73 PTGS2 (0.67) PTGS2PDE4BNR1H2NR1H3ALDH1A1
SCHEMBL626365 0.70 MPO (0.48) KMT2ALMNAMAPTHTTGAA
SCHEMBL29448054 0.70 MPO (0.48) KMT2ALMNAMAPTHTTGAA
SCHEMBL592300 0.70 PTGS2 (0.65) PTGS2KMT2APDE4BLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117165008-B Preparation process of flame-retardant plastic with thermal stability 佛山市索仕管道科技有限公司 2024-07-12 CN claimed
CN-117165008-A Preparation process of flame-retardant plastic with thermal stability 广东新富纳泰塑料制品有限公司 2023-12-05 CN claimed
CN-117165008-B Preparation process of flame-retardant plastic with thermal stability 佛山市索仕管道科技有限公司 2024-07-12 CN disclosed
CN-117165008-A Preparation process of flame-retardant plastic with thermal stability 广东新富纳泰塑料制品有限公司 2023-12-05 CN disclosed