Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 17/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925230 | 1.00 | DPP4 (0.52) | DPP4NOTUMTSHRSMN1; SMN2 | |
| SCHEMBL2928605 | 0.86 | NOTUM (0.46) | DPP4NOTUM | |
| SCHEMBL2928601 | 0.86 | NOTUM (0.46) | DPP4NOTUM | |
| SCHEMBL2929745 | 0.84 | DPP4 (0.47) | DPP4NOTUMSMN1; SMN2 | |
| SCHEMBL2929747 | 0.84 | DPP4 (0.47) | DPP4NOTUMSMN1; SMN2 | |
| SCHEMBL2922525 | 0.77 | DPP4 (0.52) | DPP4NOTUMSMN1; SMN2 | |
| SCHEMBL7132782 | 0.76 | ALDH1A1 (0.55) | NOTUMTSHRSMN1; SMN2 | |
| SCHEMBL7132786 | 0.76 | ALDH1A1 (0.55) | NOTUMTSHRSMN1; SMN2 | |
| SCHEMBL20080888 | 0.72 | NOTUM (0.58) | DPP4NOTUMSMN1; SMN2 | |
| SCHEMBL8320138 | 0.72 | SIRT6 (0.59) | DPP4NOTUMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41315-E1 | Modulators of dopamine neurotransmission | NSAB, FILIAL AF NEUROSEARCH SWEDEN AB (DE) | 2010-05-04 | — | — | US | disclosed |
| US-6924374-B2 | Central nervous system disorders; psychological disorders | A. CARLSSON RESEARCH AB (SE) | 2005-08-02 | — | — | US | disclosed |
| EP-1419773-A2 | 4-Phenylpiperidine derivatives as modulators of dopamine neurotransmission | A. Carlsson Research AB (SE) | 2004-05-19 | — | — | EP | disclosed |
| US-20030004169-A1 | Modulators of dopamine neurotransmission | NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE (DK) | 2003-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004169-A1 | Modulators of dopamine neurotransmission | OPRD1, OPRK1, OPRM1 | DPP4 4249/4885NOTUM 3910/4885TSHR 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.