Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771653 | 0.73 | — | — | |
| SCHEMBL28900167 | 0.64 | ALDH1A1 (0.38) | ALDH1A1LMNAPOLB | |
| SCHEMBL32681711 | 0.64 | KDM4E (0.40) | ALDH1A1LMNAPOLB | |
| SCHEMBL7234663 | 0.62 | ALDH1A1 (0.43) | ALDH1A1LMNAPOLB | |
| SCHEMBL31035868 | 0.62 | KDM4E (0.43) | ALDH1A1LMNAPOLB | |
| SCHEMBL11809950 | 0.61 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLB | |
| SCHEMBL15720375 | 0.60 | ALDH1A1 (0.31) | ALDH1A1LMNA | |
| SCHEMBL15720476 | 0.60 | ALDH1A1 (0.31) | ALDH1A1LMNA | |
| Potassium Ion SCHEMBL29102526 | 0.60 | — | — | |
| SCHEMBL81240 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139856-A | Parallel-ring compounds as Cbl-b inhibitors | 海南先声再明医药股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-117940404-A | Tricyclic compounds as Cbl-b inhibitors | 海南先声再明医药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |