Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31086379 | 0.88 | LMNA (0.37) | LTA4HKCNH2SCN9APKMLMNA | |
| SCHEMBL29254874 | 0.88 | LMNA (0.37) | LTA4HKCNH2SCN9APKMLMNA | |
| SCHEMBL29254832 | 0.82 | LTA4H (0.40) | LTA4HKCNH2SCN9APKMLMNA | |
| Hydrochloric Acid SCHEMBL29254913 | 0.81 | LTA4H (0.49) | LTA4HKCNH2SCN9APKMPPARG | |
| SCHEMBL29254867 | 0.78 | LMNA (0.46) | PKMLMNA | |
| SCHEMBL29255201 | 0.77 | PKM (0.39) | PKMLMNA | |
| SCHEMBL29255386 | 0.73 | LTA4H (0.47) | LTA4HKCNH2LMNAPPARGPTGER4 | |
| SCHEMBL29255261 | 0.70 | SCN9A (0.39) | LTA4HKCNH2SCN9ALMNAPPARG | |
| SCHEMBL31086242 | 0.70 | DRD2 (0.39) | SCN9ALMNAGRIN2B | |
| SCHEMBL31086352 | 0.70 | RXRA (0.44) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307534-A | LTA4H inhibitors and uses thereof | 上海海雁医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |