Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | PDE5A | O76074 | 1/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29464062 | 0.87 | TSHR (0.61) | TNKSSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL24159350 | 0.85 | TNKS (0.56) | TNKSSMN1; SMN2PDE5AABCC1ABCG2 | |
| SCHEMBL3343178 | 0.82 | MAPT (0.58) | SMN1; SMN2MAPTTP53ALDH1A1KDM4E | |
| SCHEMBL29488288 | 0.82 | MAPT (0.58) | SMN1; SMN2MAPTTP53ALDH1A1KDM4E | |
| SCHEMBL28601450 | 0.82 | ATM (0.57) | SMN1; SMN2ABCC1ABCG2MAPTALDH1A1 | |
| SCHEMBL8018992 | 0.79 | ALDH1A1 (0.60) | TNKSSMN1; SMN2PDE5AABCC1ABCG2 | |
| SCHEMBL4006005 | 0.77 | DHODH (0.70) | SMN1; SMN2MAPTTP53ALDH1A1KDM4E | |
| SCHEMBL1105491 | 0.77 | TSHR (0.75) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL24515181 | 0.77 | CA1 (0.64) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL5444926 | 0.76 | PDE7A (0.47) | TNKSSMN1; SMN2PDE5AABCC1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239888-A | Modularized synthesis method and application of acridine compound | 厦门大学 | 2024-06-25 | — | — | CN | disclosed |