Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744857 | 0.86 | LMNA (0.47) | LMNAKMT2ALPAR1L3MBTL1CXCL8 | |
| SCHEMBL31447156 | 0.86 | LMNA (0.47) | LMNAKMT2ALPAR1L3MBTL1CXCL8 | |
| SCHEMBL4804825 | 0.79 | CXCL8 (0.44) | LMNAKMT2ALPAR1MEN1L3MBTL1 | |
| SCHEMBL2458400 | 0.78 | MAPT (0.47) | LMNAKMT2ALPAR1RECQLKDM4E | |
| SCHEMBL13800729 | 0.78 | LMNA (0.41) | LMNAKMT2ALPAR1L3MBTL1CXCL8 | |
| SCHEMBL4131377 | 0.78 | CXCR2 (0.45) | LMNAKMT2ALPAR1L3MBTL1CXCL8 | |
| SCHEMBL30299532 | 0.78 | MAPT (0.47) | LMNAKMT2ALPAR1RECQLKDM4E | |
| SCHEMBL812723 | 0.77 | GABRA1 (0.52) | LMNAKMT2ALPAR1MEN1SMN1; SMN2 | |
| SCHEMBL1821014 | 0.76 | LMNA (0.51) | LMNAKMT2ALPAR1L3MBTL1CXCL8 | |
| Hydrochloric Acid SCHEMBL31043542 | 0.76 | MAPT (0.46) | LMNAKMT2ALPAR1RECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303525-B1 | PRODUCTION OF NOVEL PHOSPHANE LIGANDS AND USE IN CATALYTICAL REACTIONS | EVONIK DEGUSSA GMBH (DE) | 2010-09-08 | — | — | EP | disclosed |
| US-7553924-B2 | Catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY (RW) | 2009-06-30 | — | — | US | disclosed |
| US-20090163740-A1 | LIGANDS FOR METALS AS CATALYSTS FOR CARBON-CARBON BOND FORMATION | NATIONAL SUN YAT-SEN UNIVERSITY | 2009-06-25 | — | — | US | disclosed |
| US-7271276-B2 | Metal complexes for catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2007-09-18 | — | — | US | disclosed |
| US-20050288505-A1 | Metal complexes for catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY | 2005-12-29 | — | — | US | disclosed |
| US-20050288504-A1 | Ligands for metals as catalysts for carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY | 2005-12-29 | — | — | US | disclosed |
| US-20050137382-A1 | Catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163740-A1 | LIGANDS FOR METALS AS CATALYSTS FOR CARBON-CARBON BOND FORMATION | NCOR2, OXGR1, NCOR1 | LMNA 4652/4885KMT2A 2700/4885LPAR1 383/4885 |
| US-20050137382-A1 | Catalytic carbon-carbon bond formation | CBR1, NR1H2, NR1H3 | LMNA 4846/4885KMT2A 1760/4885LPAR1 351/4885 |
| US-20050288504-A1 | Ligands for metals as catalysts for carbon-carbon bond formation | NCOR2, NCOR1, NR1I2 | LMNA 4773/4885KMT2A 1591/4885LPAR1 447/4885 |
| US-20050288505-A1 | Metal complexes for catalytic carbon-carbon bond formation | CBR1, NR2C2, NCOR2 | LMNA 4807/4885KMT2A 1659/4885LPAR1 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.