Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744857 | 0.88 | LMNA (0.47) | CXCL8KMT2ALMNALPAR1L3MBTL1 | |
| SCHEMBL31447156 | 0.88 | LMNA (0.47) | CXCL8KMT2ALMNALPAR1L3MBTL1 | |
| SCHEMBL14770885 | 0.84 | L3MBTL1 (0.48) | KMT2ALMNAL3MBTL1MEN1MAPK1 | |
| SCHEMBL12152328 | 0.82 | LMNA (0.40) | CXCL8KMT2ALMNALPAR1L3MBTL1 | |
| SCHEMBL2925868 | 0.82 | MAPK1 (0.47) | CXCL8KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL13800729 | 0.79 | LMNA (0.41) | CXCL8KMT2ALMNALPAR1L3MBTL1 | |
| SCHEMBL2927809 | 0.79 | LMNA (0.41) | CXCL8KMT2ALMNALPAR1L3MBTL1 | |
| SCHEMBL30299532 | 0.79 | MAPT (0.47) | CXCL8KMT2ALMNALPAR1L3MBTL1 | |
| SCHEMBL4131377 | 0.79 | CXCR2 (0.45) | CXCL8KMT2ALMNALPAR1L3MBTL1 | |
| SCHEMBL2458400 | 0.79 | MAPT (0.47) | CXCL8KMT2ALMNALPAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442800-B2 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2008-10-28 | — | — | US | claimed |
| CN-101184711-A | Nucleophilic heterocyclic carbene derivatives of pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2008-05-21 | — | — | CN | claimed |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2006-12-21 | — | — | US | claimed |
| EP-3613504-A1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | Johnson Matthey Public Limited Company (GB) | 2020-02-26 | — | — | EP | disclosed |
| EP-3613504-A1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | Johnson Matthey Public Limited Company (GB) | 2020-02-26 | — | — | EP | disclosed |
| EP-2585216-B1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | JOHNSON MATTHEY PLC (GB) | 2019-11-20 | — | — | EP | disclosed |
| EP-2585216-B1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | JOHNSON MATTHEY PLC (GB) | 2019-11-20 | — | — | EP | disclosed |
| US-20190016742-A1 | Complexes | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-01-17 | — | — | US | disclosed |
| US-10167305-B2 | Allyl complexes for use in coupling reactions | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-01-01 | — | — | US | disclosed |
| US-10167305-B2 | Allyl complexes for use in coupling reactions | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-01-01 | — | — | US | disclosed |
| US-20170101533-A1 | NOVEL COMPOUND, COLORING COMPOSITION FOR DYEING OR TEXTILE PRINTING, INK JET INK, METHOD OF PRINTING ON FABRIC, AND DYED OR PRINTED FABRIC | FUJIFILM CORPORATION (JP) | 2017-04-13 | — | — | US | disclosed |
| CN-103037969-A | Complexes | JOHNSON MATTHEY PLC | 2013-04-10 | — | — | CN | disclosed |
| WO-2011161451-A1 | COMPLEXES | JOHNSON MATTHEY PLC (GB) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011161451-A1 | COMPLEXES | JOHNSON MATTHEY PLC (GB) | 2011-12-29 | — | — | WO | disclosed |
| US-7442800-B2 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442800-B2 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442800-B2 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2008-10-28 | — | — | US | disclosed |
| EP-1885669-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | Promerus LLC (US) | 2008-02-13 | — | — | EP | disclosed |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2006-12-21 | — | — | US | disclosed |
| WO-2006128097-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | PROMERUS LLC (US) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167305-B2 | Allyl complexes for use in coupling reactions | AP3M1, AP1M1, C9 | CXCL8 3838/4885KMT2A 2518/4885LMNA 4478/4885 |
| US-20190016742-A1 | Complexes | C5, C1S, C9 | CXCL8 4026/4885KMT2A 1612/4885LMNA 4209/4885 |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | NDC1, DDC, PDCD1LG2 | CXCL8 2485/4885KMT2A 548/4885LMNA 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.