SCHEMBL6744857

SCHEMBL6744857

CC(C)c1cccc(C(C)C)c1Nc1ccccc1Nc1c(C(C)C)cccc1C(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LPAR1 Q92633 1/20 0.46
CXCL8 P10145 5/20 0.45
GABRA1 P14867 3/20 0.44
GABRB2 P47870 2/20 0.44
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44
FAAH O00519 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
GABRB1 P18505 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2C P28335 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31447156 1.00 LMNA (0.47) LMNAKMT2AL3MBTL1LPAR1CXCL8
SCHEMBL4804825 0.88 CXCL8 (0.44) LMNAKMT2AL3MBTL1LPAR1CXCL8
SCHEMBL2458400 0.86 MAPT (0.47) LMNAKMT2AL3MBTL1LPAR1CXCL8
SCHEMBL13800729 0.86 LMNA (0.41) LMNAKMT2AL3MBTL1LPAR1CXCL8
SCHEMBL4131377 0.86 CXCR2 (0.45) LMNAKMT2AL3MBTL1LPAR1CXCL8
SCHEMBL30299532 0.86 MAPT (0.47) LMNAKMT2AL3MBTL1LPAR1CXCL8
SCHEMBL2927809 0.86 LMNA (0.41) LMNAKMT2AL3MBTL1LPAR1CXCL8
SCHEMBL812723 0.85 GABRA1 (0.52) LMNAKMT2ALPAR1GABRA1GABRB2
SCHEMBL1821014 0.85 LMNA (0.51) LMNAKMT2AL3MBTL1LPAR1CXCL8
SCHEMBL12377523 0.85 CYP3A4 (0.52) CYP1A2CYP3A4HPGDTSHRSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230137127-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-04 US disclosed
US-20230137127-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-04 US disclosed
EP-1092729-B1 POLYMERIZATION CATALYST, NOVEL TRANSITION METAL COMPOUND, AND POLYMERIZATION METHOD AND COPOLYMER USING THEM MITSUI CHEMICALS INC (JP) 2012-09-26 EP disclosed
US-8048833-B2 Catalytic antioxidants EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-11-01 US disclosed
US-8048833-B2 Catalytic antioxidants EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-11-01 US disclosed
US-20110230680-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-09-22 US disclosed
US-20110230680-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-09-22 US disclosed
US-7977286-B2 Substituted N,N'-diaryl-m-phenylenediamines impart good levels of oxidation inhibition in lubricants, hydraulic fluids; lubricant is a synthetic oil derived from a Fischer-Tropsch wax via palladium/phosphine complex coupling catalyst; engine, industrial, marine, hydraulic, aviation, driveline oils EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-07-12 US disclosed
US-7977286-B2 Substituted N,N'-diaryl-m-phenylenediamines impart good levels of oxidation inhibition in lubricants, hydraulic fluids; lubricant is a synthetic oil derived from a Fischer-Tropsch wax via palladium/phosphine complex coupling catalyst; engine, industrial, marine, hydraulic, aviation, driveline oils EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-07-12 US disclosed
US-20090048130-A1 Catalytic antioxidants EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2009-02-19 US disclosed
US-20090048130-A1 Catalytic antioxidants EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2009-02-19 US disclosed
WO-2007133462-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-11-22 WO disclosed
US-20070265178-A1 Lubricating compositions containing ashless catalytic antioxidant additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-11-15 US disclosed
US-20070265178-A1 Lubricating compositions containing ashless catalytic antioxidant additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-11-15 US disclosed
US-6703459-B1 ORGANIC TRANSITION METAL COMPLEXES HAVING SPECIFIC STRUCTURE, WHICH CAN FORM COPOLYMERS HAVING LINKAGE FORMED BY MIGRATION OF ACTIVE HYDROGEN OF UNSATURATED MONOMER MITSUI CHEMICALS, INC. (JP) 2004-03-09 US disclosed
EP-1092729-A1 POLYMERIZATION CATALYST, NOVEL TRANSITION METAL COMPOUND, AND POLYMERIZATION METHOD AND COPOLYMER USING THEM Mitsui Chemicals, Inc. (JP) 2001-04-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265178-A1 Lubricating compositions containing ashless catalytic antioxidant additives GPX4, SOD1, GPX1 LMNA 3619/4885KMT2A 2516/4885L3MBTL1 4142/4885
US-20230137127-A1 ORGANIC LIGHT-EMITTING DEVICE L1CAM, CHRM1, CHRM2 LMNA 1881/4885KMT2A 3190/4885L3MBTL1 10/4885
US-20110230680-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES GPX4, SOD1, GPX1 LMNA 3636/4885KMT2A 2509/4885L3MBTL1 4201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.