Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31447156 | 0.85 | LMNA (0.47) | LMNAKMT2ALPAR1CXCL8SMN1; SMN2 | |
| SCHEMBL6744857 | 0.85 | LMNA (0.47) | LMNAKMT2ALPAR1CXCL8SMN1; SMN2 | |
| SCHEMBL4804825 | 0.78 | CXCL8 (0.44) | LMNAKMT2ALPAR1CXCL8MAPT | |
| SCHEMBL21817077 | 0.77 | MAPT (0.58) | LMNAKMT2ARAB9ALPAR1CXCL8 | |
| SCHEMBL4131377 | 0.76 | CXCR2 (0.45) | LMNAKMT2ALPAR1CXCL8SMN1; SMN2 | |
| SCHEMBL30299532 | 0.76 | MAPT (0.47) | LMNAKMT2ARAB9ALPAR1CXCL8 | |
| SCHEMBL2458400 | 0.76 | MAPT (0.47) | LMNAKMT2ARAB9ALPAR1CXCL8 | |
| SCHEMBL2927809 | 0.76 | LMNA (0.41) | LMNAKMT2ANPC1RAB9ALPAR1 | |
| SCHEMBL13800729 | 0.76 | LMNA (0.41) | LMNAKMT2ALPAR1CXCL8SMN1; SMN2 | |
| SCHEMBL20520525 | 0.76 | L3MBTL1 (0.45) | LMNAKMT2ANPC1RAB9ALPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117550986-A | Tropone ligand compound, metal complex and application thereof | 合肥中科科乐新材料有限责任公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-2315788-B1 | METAL-LIGAND COMPLEXES AND CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-11-13 | — | — | EP | disclosed |
| EP-2536735-B1 | METAL-LIGAND COMPLEXES AND CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-08-01 | — | — | EP | disclosed |
| US-8372927-B2 | Metal-ligand complexes and catalysts | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-02-12 | — | — | US | disclosed |
| US-8372927-B2 | Metal-ligand complexes and catalysts | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-02-12 | — | — | US | disclosed |
| EP-2536735-A1 | METAL-LIGAND COMPLEXES AND CATALYSTS | Dow Global Technologies LLC (US) | 2012-12-26 | — | — | EP | disclosed |
| CN-102822180-A | Metal Ligand Complexes and Catalysts | DOW GLOBAL TECHNOLOGIES LLC | 2012-12-12 | — | — | CN | disclosed |
| US-8202954-B2 | Metal-ligand complexes and catalysts | DOW GLOBAL TECHNOLOGIES LLC | 2012-06-19 | — | — | US | disclosed |
| US-8202954-B2 | Metal-ligand complexes and catalysts | DOW GLOBAL TECHNOLOGIES LLC | 2012-06-19 | — | — | US | disclosed |
| WO-2011102989-A1 | METAL-LIGAND COMPLEXES AND CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-08-25 | — | — | WO | disclosed |
| US-20110207902-A1 | METAL-LIGAND COMPLEXES AND CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC | 2011-08-25 | — | — | US | disclosed |
| EP-2315788-A2 | METAL-LIGAND COMPLEXES AND CATALYSTS | Dow Global Technologies LLC (US) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010022228-A2 | METAL-LIGAND COMPLEXES AND CATALYSTS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| US-20100048842-A1 | METAL-LIGAND COMPLEXES AND CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC | 2010-02-25 | — | — | US | disclosed |
| US-20100048842-A1 | METAL-LIGAND COMPLEXES AND CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC | 2010-02-25 | — | — | US | disclosed |
| US-7375242-B2 | Catalysts for olefin polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| US-20030027957-A1 | Catalysts for olefin polymerization | HICKS FREDERICK (US) | 2003-02-06 | — | — | US | disclosed |
| US-6451940-B1 | THE USE OF AMINOTROPONES AS LIGANDS FOR NICKEL CONTAINING OLEFIN POLYMERIZATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-09-17 | — | — | US | disclosed |
| EP-1237951-A1 | CATALYSTS FOR OLEFIN POLYMERIZATIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001030865-A1 | CATALYSTS FOR OLEFIN POLYMERIZATIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207902-A1 | METAL-LIGAND COMPLEXES AND CATALYSTS | ZC3HAV1L, FARS2, ACSL4 | LMNA 3548/4885KMT2A 2882/4885NPC1 3024/4885 |
| US-20100048842-A1 | METAL-LIGAND COMPLEXES AND CATALYSTS | ZC3HAV1L, FARS2, ACSL4 | LMNA 3548/4885KMT2A 2882/4885NPC1 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.