SCHEMBL292813

SCHEMBL292813

COc1ccc(COC(=O)O)cc1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.60
ALDH1A1 P00352 2/20 0.56
CA2 P00918 5/20 0.55
GAA P10253 3/20 0.53
KMT2A Q03164 3/20 0.53
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
HPGD P15428 1/20 0.53
CA1 P00915 4/20 0.51
CA9 Q16790 4/20 0.51
CA12 O43570 3/20 0.51
NPSR1 Q6W5P4 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA7 P43166 1/20 0.50
TPMT P51580 1/20 0.50
CA14 Q9ULX7 1/20 0.50
NPC1 O15118 1/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29453853 1.00 LDHA (0.60) LDHAALDH1A1CA2GAAKMT2A
SCHEMBL292812 0.87 ALDH1A1 (0.57) LDHAALDH1A1CA2GAAKMT2A
SCHEMBL12311379 0.86 TSHR (0.66) ALDH1A1GAACA9CA12CA4
SCHEMBL6481775 0.86 ALDH1A1 (0.56) LDHAALDH1A1CA2GAAKMT2A
SCHEMBL6403426 0.86 ALDH1A1 (0.56) LDHAALDH1A1CA2GAAKMT2A
SCHEMBL28624213 0.86 ALDH1A1 (0.56) LDHAALDH1A1CA2GAAKMT2A
SCHEMBL27728485 0.84 ALDH1A1 (0.58) LDHAALDH1A1CA2GAAKMT2A
SCHEMBL308571 0.84 ALDH1A1 (0.54) LDHAALDH1A1CA2GAAKMT2A
SCHEMBL6481771 0.84 ALDH1A1 (0.54) LDHAALDH1A1CA2GAAKMT2A
SCHEMBL8894595 0.83 KMT2A (0.56) LDHAALDH1A1KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF ZIKANI THERAPEUTICS INC (US) 2026-02-05 US claimed
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US claimed
US-11634449-B2 Macrolides and methods of their preparation and use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-04-25 US claimed
EP-3649135-B1 SYNTHESIS OF HALICHONDRINS HARVARD COLLEGE (US) 2022-12-28 EP claimed
US-20220332747-A1 MACROLIDES AND METHODS OF THEIR PREPARATION AND USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-10-20 US claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
US-11241435-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis THE GENERAL HOSPITAL CORPORATION (US) 2022-02-08 US claimed
EP-3172213-B1 MACROCYCLIC KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2021-09-22 EP claimed
EP-3171874-B1 IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2020-11-18 EP claimed
EP-3063164-B1 SYNTHETIC ROUTE TO 2'-DEOXY-2',2'-DIFLUOROTETRAHYDROURIDINES OTSUKA PHARMA CO LTD (JP) 2018-12-05 EP claimed
EP-2727915-B1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof CONCERT PHARMACEUTICALS INC (US) 2016-04-13 EP claimed
CN-103214409-B The synthesis of tsiklomitsin and analogue thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-10-21 CN claimed
EP-2727915-A1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof Concert Pharmaceuticals Inc. (US) 2014-05-07 EP claimed
CN-101027279-B Synthesis of tetracyclines and analogues thereof HARVARD COLLEGE 2013-03-27 CN claimed
US-12637463-B2 Tricyclic kinase inhibitors and uses thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-05-26 US disclosed
US-12637453-B2 Pyrazolopyridine inhibitors of c-Jun-n-Terminal kinases and uses thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-05-26 US disclosed
US-20260137806-A1 INTERCALATING SUGAR MOLECULES XALUD THERAPEUTICS, INC. (US) 2026-05-21 US disclosed
EP-0318060-A2 Griseolic acid derivatives, their preparation and their use Sankyo Company Limited (JP) 1989-05-31 EP disclosed
EP-0251827-A2 New cyclic ether derivatives, their preparation and their use Sankyo Company Limited (JP) 1988-01-07 EP disclosed
EP-0214708-A2 Griseolic acid derivatives, their preparation and their use SANKYO COMPANY LIMITED (JP) 1987-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637463-B2 Tricyclic kinase inhibitors and uses thereof CDK1, CDK11A, CDK11B LDHA 2423/4885ALDH1A1 2753/4885CA2 1119/4885
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF MALT1, CCR10, CYP51A1 LDHA 1776/4885ALDH1A1 1752/4885CA2 3285/4885
US-20220332747-A1 MACROLIDES AND METHODS OF THEIR PREPARATION AND USE CYP11B2, ERG28, DHCR7 LDHA 2681/4885ALDH1A1 1071/4885CA2 4851/4885
US-11634449-B2 Macrolides and methods of their preparation and use CYP11B2, ERG28, DHCR7 LDHA 2681/4885ALDH1A1 1071/4885CA2 4851/4885
US-11241435-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis SOST, SIK2, SIK1 LDHA 4089/4885ALDH1A1 4790/4885CA2 681/4885
US-20260137806-A1 INTERCALATING SUGAR MOLECULES SLC2A1, SLC2A2, SLC2A4 LDHA 30/4885ALDH1A1 542/4885CA2 1749/4885
US-12637453-B2 Pyrazolopyridine inhibitors of c-Jun-n-Terminal kinases and uses thereof MAP3K1, MAP3K3, MAPK1 LDHA 1543/4885ALDH1A1 1172/4885CA2 2079/4885
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents ROS1, NOX4, NOX5 LDHA 2895/4885ALDH1A1 348/4885CA2 3322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.