Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353984 | 0.69 | MAPT (0.33) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL3739493 | 0.69 | ALDH1A1 (0.44) | ALOX15ALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL31074229 | 0.69 | CES2 (0.56) | LMNACES2CES1ALDH1A1MAPT | |
| SCHEMBL28754170 | 0.68 | ALDH1A1 (0.37) | LMNAALOX15ALDH1A1MAPTNPC1 | |
| SCHEMBL29527999 | 0.68 | ALDH1A1 (0.37) | LMNAALOX15ALDH1A1MAPTNPC1 | |
| SCHEMBL2239464 | 0.67 | KDM4E (0.40) | ALOX15ALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL3747840 | 0.65 | GAA (0.44) | ALDH1A1MAPTTDP1NPC1RAB9A | |
| SCHEMBL30546824 | 0.65 | MAPT (0.34) | LMNAALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL5355939 | 0.64 | — | — | |
| SCHEMBL21718806 | 0.64 | CA2 (0.39) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118284614-A | Diaryloxybenzobisoxazole compounds disubstituted with thienothiophene groups | 埃尼股份公司 | 2024-07-02 | — | — | CN | disclosed |