Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15953453 | 0.81 | MAPK1 (0.69) | PGRL3MBTL1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL10186886 | 0.81 | L3MBTL1 (0.83) | PGRL3MBTL1MAPTMAPK1ALDH1A1 | |
| SCHEMBL5622356 | 0.78 | PGR (0.79) | PGRL3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL29956809 | 0.77 | RAB9A (0.51) | L3MBTL1SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL957571 | 0.77 | RAB9A (0.51) | L3MBTL1SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL27179416 | 0.76 | SIRT2 (0.84) | SMN1; SMN2MAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL29956254 | 0.76 | TAS2R14 (0.53) | PGRENPP2 | |
| SCHEMBL12539143 | 0.75 | MGLL (0.41) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29951094 | 0.75 | MGLL (0.41) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7267305 | 0.74 | PGR (0.82) | PGRL3MBTL1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118339145-A | Bicyclic fused ring derivatives or salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-12 | — | — | CN | disclosed |