Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534913 | 0.93 | MAPT (0.77) | PGRL3MBTL1MAPTMCOLN3KEAP1 | |
| SCHEMBL6534675 | 0.92 | PGR (0.71) | PGRL3MBTL1MAPTMCOLN3KEAP1 | |
| SCHEMBL10186886 | 0.91 | L3MBTL1 (0.83) | PGRL3MBTL1MAPTMCOLN3KEAP1 | |
| SCHEMBL7267305 | 0.91 | PGR (0.82) | PGRL3MBTL1MAPTMCOLN3KEAP1 | |
| SCHEMBL664705 | 0.87 | PGR (0.68) | PGRL3MBTL1MAPTHPGDALDH1A1 | |
| SCHEMBL15482244 | 0.84 | HPGD (0.69) | PGRMAPTHPGDALDH1A1MEN1 | |
| SCHEMBL691734 | 0.82 | ALDH1A1 (0.73) | PGRL3MBTL1MAPTKEAP1ALDH1A1 | |
| SCHEMBL2117796 | 0.81 | PGR (0.56) | PGRL3MBTL1MAPTMCOLN3KEAP1 | |
| SCHEMBL13577032 | 0.81 | PGR (0.56) | PGRL3MBTL1MCOLN3KEAP1HPGD | |
| SCHEMBL6321497 | 0.80 | PGR (0.54) | PGRL3MBTL1MAPTKEAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021495-A1 | SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021495-A1 | SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR | ESR1, ESR2, GPER1 | PGR 22/4885L3MBTL1 4730/4885MAPT 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.