Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.31 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29290943 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1POLBALKBH2EGLN1 | |
| SCHEMBL28099962 | 0.78 | CRBN (0.35) | KDM4EALDH1A1POLBALKBH2EGLN1 | |
| SCHEMBL28209858 | 0.78 | SMN1; SMN2 (0.34) | KDM4EALDH1A1NPSR1POLBALKBH2 | |
| SCHEMBL29290952 | 0.78 | SMN1; SMN2 (0.41) | KDM4EALDH1A1THRBPOLBALKBH2 | |
| SCHEMBL29290948 | 0.74 | SLC11A2 (0.34) | KDM4EPOLBPDCD1CD274SLC11A2 | |
| SCHEMBL27520939 | 0.68 | PTGS2 (0.36) | KDM4ECSNK2A1NPSR1SMN1; SMN2 | |
| SCHEMBL27504274 | 0.67 | POLB (0.37) | KDM4EALDH1A1POLBPDCD1CD274 | |
| SCHEMBL28565280 | 0.67 | SMN1; SMN2 (0.34) | KDM4EALDH1A1NPSR1POLBSMN1; SMN2 | |
| SCHEMBL28811086 | 0.65 | CHRM2 (0.35) | KDM4EALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL28545490 | 0.64 | KDM4E (0.40) | KDM4EALDH1A1CSNK2A1NPSR1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678854-A | A kind of method that manganese catalyzes and synthesizes pyrido [1,2-a] indoles -6 (1H) -one class compound | 陕西师范大学 | 2019-04-26 | — | — | CN | disclosed |