Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18914456 | 0.81 | EPHX2 (0.42) | EPHX2TDP1MAOAMAOBMEN1 | |
| SCHEMBL13329078 | 0.80 | KDM4E (0.50) | EPHX2TDP1MAOAMAOBMEN1 | |
| SCHEMBL31226873 | 0.77 | EPHX2 (0.44) | EPHX2TDP1MAOAMAOBMEN1 | |
| SCHEMBL27437838 | 0.76 | TDP1 (0.62) | EPHX2TDP1MAOAMAOBMEN1 | |
| SCHEMBL26004385 | 0.75 | MLYCD (0.39) | EPHX2TDP1MAOAMAOBMEN1 | |
| SCHEMBL18354072 | 0.74 | ZDHHC20 (0.50) | EPHX2TDP1MAOAMAOBMEN1 | |
| SCHEMBL1964429 | 0.73 | ALDH1A1 (0.50) | EPHX2TDP1MAOAMAOBMEN1 | |
| SCHEMBL25525668 | 0.73 | MAOA (0.42) | EPHX2TDP1MAOAMAOBMEN1 | |
| SCHEMBL20674794 | 0.73 | EPHX2 (0.41) | EPHX2TDP1MAOAMAOBMEN1 | |
| SCHEMBL9891443 | 0.73 | MAOA (0.46) | EPHX2TDP1MAOAMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689107-A | Derivatives of amatoxins and their coupling to cell binding molecules | 杭州多禧生物科技有限公司 | 2019-04-26 | — | — | CN | disclosed |