Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291334 | 0.87 | LMNA (0.49) | ALDH1A1KMT2AMEN1CYP3A4LMNA | |
| SCHEMBL29291326 | 0.85 | NPC1 (0.51) | ALDH1A1MAPTGAAPOLBNPC1 | |
| SCHEMBL29291328 | 0.85 | LMNA (0.52) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL29291333 | 0.84 | LMNA (0.50) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL29291323 | 0.82 | CES2 (0.49) | NPC1RAB9ACYP3A4LMNASMN1; SMN2 | |
| SCHEMBL29291340 | 0.80 | CES2 (0.46) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL29291321 | 0.79 | MAPT (0.56) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| SCHEMBL28118973 | 0.77 | MAPT (0.60) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| SCHEMBL29291325 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL812736 | 0.75 | LMNA (0.67) | ALDH1A1MAPTKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761842-B | Synthesis method of alpha-F-beta-NHAc-carbonyl compound | 浙江工业大学 | 2021-11-30 | — | — | CN | disclosed |