Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291334 | 0.91 | LMNA (0.49) | LMNATP53KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL29291326 | 0.89 | NPC1 (0.51) | LMNATP53ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL29291333 | 0.87 | LMNA (0.50) | LMNATP53KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL29291325 | 0.85 | SMN1; SMN2 (0.46) | LMNATP53KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL29291323 | 0.85 | CES2 (0.49) | LMNATP53SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29291338 | 0.85 | ALDH1A1 (0.50) | LMNATP53ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL29291340 | 0.83 | CES2 (0.46) | LMNATP53ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL76895 | 0.79 | LMNA (0.50) | LMNATP53ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL29291311 | 0.77 | CES2 (0.47) | LMNATP53KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL29291330 | 0.76 | GPR139 (0.44) | LMNAALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761842-B | Synthesis method of alpha-F-beta-NHAc-carbonyl compound | 浙江工业大学 | 2021-11-30 | — | — | CN | disclosed |