Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291334 | 0.87 | LMNA (0.49) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29291328 | 0.85 | LMNA (0.52) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL29291326 | 0.80 | NPC1 (0.51) | SMN1; SMN2POLBMAPTLMNAALDH1A1 | |
| SCHEMBL29291333 | 0.78 | LMNA (0.50) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29291323 | 0.76 | CES2 (0.49) | SMN1; SMN2LMNATP53NPC1RAB9A | |
| SCHEMBL29291338 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2POLBMEN1KMT2AMAPT | |
| SCHEMBL11587933 | 0.75 | CES2 (0.67) | SMN1; SMN2GPR139POLBMEN1KMT2A | |
| SCHEMBL29291340 | 0.74 | CES2 (0.46) | SMN1; SMN2POLBMEN1KMT2AMAPT | |
| SCHEMBL29291330 | 0.73 | GPR139 (0.44) | GPR139POLBMEN1KMT2AMAPT | |
| SCHEMBL29291324 | 0.73 | ALDH1A1 (0.55) | SMN1; SMN2POLBMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761842-B | Synthesis method of alpha-F-beta-NHAc-carbonyl compound | 浙江工业大学 | 2021-11-30 | — | — | CN | disclosed |