Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291334 | 0.90 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2HDAC1KMT2A | |
| SCHEMBL29291328 | 0.87 | LMNA (0.52) | LMNAALDH1A1SMN1; SMN2HDAC1KMT2A | |
| SCHEMBL29291326 | 0.87 | NPC1 (0.51) | LMNAALDH1A1SMN1; SMN2HDAC1CYP3A4 | |
| SCHEMBL29291338 | 0.84 | ALDH1A1 (0.50) | LMNAALDH1A1CYP1A2SMN1; SMN2KMT2A | |
| SCHEMBL29291323 | 0.84 | CES2 (0.49) | LMNACYP1A2SMN1; SMN2HDAC1CYP3A4 | |
| SCHEMBL29291340 | 0.82 | CES2 (0.46) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29291324 | 0.81 | ALDH1A1 (0.55) | LMNAALDH1A1CYP1A2SMN1; SMN2HDAC1 | |
| SCHEMBL29291325 | 0.78 | SMN1; SMN2 (0.46) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29291317 | 0.76 | LMNA (0.46) | LMNAALDH1A1SMN1; SMN2HDAC1KMT2A | |
| SCHEMBL29291330 | 0.75 | GPR139 (0.44) | LMNAALDH1A1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761842-B | Synthesis method of alpha-F-beta-NHAc-carbonyl compound | 浙江工业大学 | 2021-11-30 | — | — | CN | disclosed |