SCHEMBL29308618

SCHEMBL29308618

CC1c2c(-n3cc[nH]c3=O)c(Br)nn2CCN1C(=O)OC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SETD7 Q8WTS6 1/20 0.31
▸ SPR P35270 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24276763 0.82 LMNA (0.30) —
SCHEMBL31692376 0.78 LMNA (0.32) —
SCHEMBL31616897 0.78 MAPK1 (0.34) SPR
SCHEMBL29308619 0.75 MAP4K4 (0.36) SETD7
SCHEMBL30622817 0.75 ALDH1A1 (0.33) SETD7
SCHEMBL30622860 0.72 GPR119 (0.40) SETD7
SCHEMBL29308615 0.72 KCNH2 (0.38) —
SCHEMBL24276775 0.68 USP30 (0.33) SETD7
SCHEMBL34466050 0.67 GRM5 (0.34) SETD7
SCHEMBL26026951 0.67 GRM5 (0.36) SETD7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037339-B2 Substituted imidazoles as GLP-1 receptor agonists ECCOGENE INC. (US) 2024-07-16 — — US disclosed
US-12037339-B2 Substituted imidazoles as GLP-1 receptor agonists ECCOGENE INC. (US) 2024-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037339-B2 Substituted imidazoles as GLP-1 receptor agonists GLP1R, GIPR, SLC5A1 SETD7 2761/4885SPR 1869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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