Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.33 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29308619 | 0.85 | MAP4K4 (0.36) | ALDH1A1GPR119SETD7MAP4K4UCHL1 | |
| SCHEMBL26645533 | 0.83 | — | — | |
| SCHEMBL30622860 | 0.82 | GPR119 (0.40) | GPR119SETD7MAP4K4UCHL1 | |
| SCHEMBL29308615 | 0.81 | KCNH2 (0.38) | ALDH1A1GPR119UCHL1 | |
| SCHEMBL30622862 | 0.78 | CSNK1D (0.37) | ALDH1A1SETD7HDAC1 | |
| SCHEMBL26645130 | 0.78 | CSNK1D (0.37) | ALDH1A1SETD7HDAC1 | |
| SCHEMBL26645124 | 0.76 | NR1H2 (0.40) | GPR119SETD7NR1H2NR1H3 | |
| SCHEMBL30622921 | 0.76 | NR1H2 (0.40) | GPR119SETD7NR1H2NR1H3 | |
| SCHEMBL29308618 | 0.75 | SETD7 (0.31) | SETD7 | |
| SCHEMBL30622784 | 0.74 | SETD7 (0.34) | GPR119SETD7MAP4K4HDAC1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |