Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.35 |
| ▸ | BUB1 | O43683 | 2/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645255 | 0.85 | SMO (0.34) | NPC1 | |
| SCHEMBL30622831 | 0.83 | MAPK14 (0.43) | GPR119 | |
| SCHEMBL30623087 | 0.82 | HTT (0.39) | GPR119USP30MMP13 | |
| SCHEMBL30622817 | 0.82 | ALDH1A1 (0.33) | GPR119SETD7UCHL1MAP4K4 | |
| SCHEMBL29308619 | 0.82 | MAP4K4 (0.36) | GPR119SETD7UCHL1MAP4K4 | |
| SCHEMBL30622743 | 0.79 | USP30 (0.39) | GPR119USP30MMP13SETD7BUB1 | |
| SCHEMBL30622869 | 0.79 | USP30 (0.39) | GPR119USP30MMP13SETD7BUB1 | |
| SCHEMBL26645802 | 0.79 | USP30 (0.39) | GPR119USP30MMP13SETD7BUB1 | |
| SCHEMBL30622978 | 0.78 | CYP3A4 (0.39) | GPR119USP30MAP4K4 | |
| SCHEMBL30622876 | 0.77 | GHSR (0.44) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |