SCHEMBL29313282

SCHEMBL29313282

CCC(=O)CCC(=O)NCC(O)CN

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 2/20 0.33
GABRR1 P24046 2/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
ASAH1 Q13510 1/20 0.32
FAAH O00519 1/20 0.31
MMP2 P08253 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
DNM1 Q05193 1/20 0.31
P2RY10 O00398 1/20 0.30
GPR174 Q9BXC1 1/20 0.30
TPSAB1 Q15661 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24462473 0.83 CTSD (0.45) TLR2GABRR1ALDH1A1LMNAASAH1
SCHEMBL22814737 0.81 ALDH1A1 (0.39) TLR2GABRR1ALDH1A1LMNAASAH1
SCHEMBL22123634 0.79 MMP2 (0.46) TLR2GABRR1ALDH1A1LMNAASAH1
SCHEMBL13351409 0.77 FAAH (0.56) TLR2ASAH1FAAHDNM1P2RY10
SCHEMBL22821244 0.77 ALDH1A1 (0.32) GABRR1ALDH1A1LMNAMMP2
SCHEMBL22123760 0.74 MMP2 (0.42) GABRR1LMNAMMP2
SCHEMBL16985031 0.74 GABRR1 (0.34) GABRR1ALDH1A1LMNAMMP2
SCHEMBL16984997 0.73 TERT (0.37) TLR2ASAH1FAAHDNM1P2RY10
SCHEMBL1174781 0.73 MEN1 (0.41) ALDH1A1LMNAFAAHTDP1DNM1
SCHEMBL16984927 0.73 GABRR1 (0.33) GABRR1LMNAMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024146902-A1 METHODS OF PRODUCING HYDROGEL MICROSPHERES ASCENDIS PHARMA A/S (DK) 2024-07-11 WO disclosed
WO-2024146920-A1 DRUG CONJUGATES FOR THE TREATMENT OF OCULAR DISORDERS ASCENDIS PHARMA OPHTHALMOLOGY DIVISION A/S (DK) 2024-07-11 WO disclosed