Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ABL2 | P42684 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.39 |
| ▸ | MAP3K8 | P41279 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313569 | 0.77 | TNK2 (0.48) | ABL1SRCMAP3K8 | |
| SCHEMBL29314449 | 0.76 | CHEK1 (0.49) | LRRK2PRKCQMAP3K8 | |
| SCHEMBL29313573 | 0.74 | LRRK2 (0.47) | LRRK2PRKCQ | |
| SCHEMBL23019347 | 0.70 | PRKCQ (0.41) | LRRK2PRKCQ | |
| SCHEMBL29313773 | 0.70 | CCNA2 (0.46) | LRRK2PRKCQ | |
| SCHEMBL12824668 | 0.70 | CHRNB2 (0.48) | KAT2BCHRNB2CHRNA3 | |
| SCHEMBL18494148 | 0.69 | KAT2B (0.48) | KAT2BABL1SRCCHRNB2CHRNA3 | |
| SCHEMBL22767998 | 0.69 | CHRNB2 (0.49) | KAT2BCHRNB2CHRNA3 | |
| SCHEMBL15072064 | 0.68 | CDK19 (0.56) | — | |
| SCHEMBL29313606 | 0.68 | PTK2 (0.40) | LRRK2PRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |