Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.59 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TARS1 | P26639 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317764 | 0.87 | PPARA (0.45) | PPARALMNASMN1; SMN2CA2TARS1 | |
| SCHEMBL29321248 | 0.85 | CA1 (0.48) | PPARASMN1; SMN2HTTCA2PTGS1 | |
| SCHEMBL29317748 | 0.84 | MMP2 (0.50) | PPARALMNASMN1; SMN2CA2EGFR | |
| SCHEMBL29317750 | 0.84 | PPARA (0.43) | PPARALMNASMN1; SMN2MAPTGAA | |
| SCHEMBL29317752 | 0.84 | F2 (0.45) | PPARALARS1LMNACA2 | |
| SCHEMBL29317754 | 0.84 | LARS1 (0.53) | PPARALARS1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL29317746 | 0.83 | MMP1 (0.48) | PPARACA2 | |
| SCHEMBL29321247 | 0.83 | PPARA (0.42) | PPARAMITFLMNAHPGDKMT2A | |
| SCHEMBL29321254 | 0.82 | CA1 (0.52) | PPARALMNASMN1; SMN2MAPTHTT | |
| SCHEMBL29317687 | 0.82 | MMP13 (0.47) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |