Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317683 | 0.84 | PPARA (0.59) | LARS1LMNAGAASMN1; SMN2PPARA | |
| SCHEMBL17943496 | 0.82 | L3MBTL1 (0.58) | LARS1NLRP3L3MBTL1RAPGEF3ALDH1A1 | |
| SCHEMBL29317756 | 0.81 | FLT1 (0.50) | L3MBTL1ALDH1A1LMNAGAAPPARA | |
| SCHEMBL29317748 | 0.80 | MMP2 (0.50) | ALDH1A1LMNASMN1; SMN2PPARASLC1A3 | |
| SCHEMBL29317764 | 0.80 | PPARA (0.45) | ALDH1A1LMNAGAASMN1; SMN2PPARA | |
| SCHEMBL29317750 | 0.80 | PPARA (0.43) | LMNAGAASMN1; SMN2PPARAKAT6A | |
| SCHEMBL29317752 | 0.80 | F2 (0.45) | LARS1ALDH1A1LMNAPPARAKAT6A | |
| SCHEMBL29321248 | 0.79 | CA1 (0.48) | L3MBTL1ALDH1A1GAASMN1; SMN2PPARA | |
| SCHEMBL15219093 | 0.79 | RAB9A (0.54) | L3MBTL1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL3469824 | 0.77 | F2 (0.56) | LARS1NLRP3L3MBTL1RAPGEF3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |