SCHEMBL29317764

SCHEMBL29317764

CC(C)OC(C)(C)C(=O)NS(=O)(=O)c1ccc(O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.45
ADAMTS4 O75173 1/20 0.43
UQCRB P14927 1/20 0.42
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.40
POLB P06746 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
GAA P10253 1/20 0.40
GFER P55789 1/20 0.40
ELANE P08246 1/20 0.40
NPSR1 Q6W5P4 1/20 0.38
DHFR P00374 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ENPP2 Q13822 1/20 0.37
TARS1 P26639 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29321248 0.87 CA1 (0.48) PPARAALDH1A1POLBSMN1; SMN2GAA
SCHEMBL29317683 0.87 PPARA (0.59) PPARALMNASMN1; SMN2GAATARS1
SCHEMBL29317748 0.86 MMP2 (0.50) PPARAALDH1A1LMNASMN1; SMN2GFER
SCHEMBL29321247 0.85 PPARA (0.42) PPARAALDH1A1LMNASMN1; SMN2NPSR1
SCHEMBL29317746 0.85 MMP1 (0.48) PPARAADAMTS4CA1CA2
SCHEMBL29317687 0.83 MMP13 (0.47) PPARAADAMTS4
SCHEMBL29321254 0.83 CA1 (0.52) PPARAADAMTS4ALDH1A1LMNAPOLB
SCHEMBL29317754 0.80 LARS1 (0.53) PPARAALDH1A1LMNAPOLBSMN1; SMN2
SCHEMBL29317750 0.77 PPARA (0.43) PPARALMNASMN1; SMN2GAA
SCHEMBL29317752 0.77 F2 (0.45) PPARAALDH1A1LMNAPOLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024145931-A1 SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF 上海医药工业研究院有限公司 2024-07-11 WO disclosed