Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317756 | 0.86 | FLT1 (0.50) | PPARAPOLBALDH1A1LMNAKAT6A | |
| SCHEMBL29317750 | 0.85 | PPARA (0.43) | PPARALMNAKAT6A | |
| SCHEMBL29317683 | 0.84 | PPARA (0.59) | PPARACA2LMNALARS1 | |
| SCHEMBL8549266 | 0.82 | F2 (0.51) | F2PRSS1PRSS2PRSS3POLB | |
| SCHEMBL29317753 | 0.81 | BCL9 (0.46) | PPARAFBP1KAT6A | |
| SCHEMBL29317754 | 0.80 | LARS1 (0.53) | F2PRSS1PRSS2PRSS3PPARA | |
| SCHEMBL29317748 | 0.77 | MMP2 (0.50) | PPARAALDH1A1HSD17B10CA2LMNA | |
| SCHEMBL29317764 | 0.77 | PPARA (0.45) | PPARAPOLBALDH1A1TSHRTDP1 | |
| SCHEMBL9302922 | 0.76 | F2 (0.51) | F2PRSS1PRSS2PRSS3POLB | |
| SCHEMBL8589883 | 0.76 | ALDH1A1 (0.67) | F2PRSS1PRSS2PRSS3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |