Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 3/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | BRD1 | O95696 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317687 | 0.85 | MMP13 (0.47) | BCL9CTNNB1ADAMTS4PPARABRPF1 | |
| SCHEMBL19006934 | 0.83 | KAT6A (0.50) | KAT6ATRIM24MAPTPGRRXFP1 | |
| SCHEMBL29317752 | 0.81 | F2 (0.45) | KAT6APPARAFBP1 | |
| SCHEMBL29317750 | 0.81 | PPARA (0.43) | KAT6AMAPTPGRPPARA | |
| SCHEMBL29317683 | 0.81 | PPARA (0.59) | MAPTPPARA | |
| SCHEMBL29317756 | 0.81 | FLT1 (0.50) | KAT6AMAPTPGRPPARA | |
| SCHEMBL29317754 | 0.77 | LARS1 (0.53) | KAT6AMAPTPPARA | |
| SCHEMBL17127741 | 0.76 | KAT6A (0.53) | KAT6ATRIM24MAPTPGRRXFP1 | |
| SCHEMBL29317764 | 0.74 | PPARA (0.45) | ADAMTS4PPARA | |
| SCHEMBL29321248 | 0.73 | CA1 (0.48) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |