Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.45 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.45 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.45 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.45 |
| ▸ | RORA | P35398 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317752 | 0.86 | F2 (0.45) | LMNAALDH1A1POLBPPARAKAT6A | |
| SCHEMBL29317748 | 0.84 | MMP2 (0.50) | FLT1FLT4KDRLMNAALDH1A1 | |
| SCHEMBL29054081 | 0.84 | PPARA (0.65) | FLT1FLT4KDRMEP1BLMNA | |
| SCHEMBL29317750 | 0.84 | PPARA (0.43) | LMNAPPARAABCC9ABCC8KCNJ11 | |
| SCHEMBL29317683 | 0.83 | PPARA (0.59) | LMNAPPARAGAAMAPT | |
| SCHEMBL29317754 | 0.81 | LARS1 (0.53) | LMNAALDH1A1POLBPPARAKAT6A | |
| SCHEMBL29317753 | 0.81 | BCL9 (0.46) | PPARAKAT6APGRMAPT | |
| SCHEMBL30498774 | 0.79 | FLT1 (0.56) | FLT1FLT4KDRMEP1BALDH1A1 | |
| SCHEMBL2317611 | 0.77 | FLT1 (0.60) | FLT1FLT4KDRMEP1BALDH1A1 | |
| SCHEMBL29317764 | 0.76 | PPARA (0.45) | LMNAALDH1A1POLBPPARAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |