SCHEMBL7047441

SCHEMBL7047441

C=CC(=O)NC(=O)c1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.52
ALDH1A1 P00352 3/20 0.52
LMNA P02545 2/20 0.52
KDM4E B2RXH2 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
PTGS2 P35354 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.45
ALOX12 P18054 2/20 0.45
EPHX1 P07099 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTT P42858 1/20 0.45
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
RXFP1 Q9HBX9 1/20 0.44
POLB P06746 1/20 0.44
FLT1 P17948 1/20 0.44
FLT4 P35916 1/20 0.44
KDR P35968 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23639730 0.85 MAPT (0.52) MAPTALDH1A1LMNAKDM4EL3MBTL1
SCHEMBL15047786 0.81 MAPT (0.67) MAPTALDH1A1LMNAKDM4EL3MBTL1
SCHEMBL17997805 0.81 LMNA (0.50) MAPTALDH1A1LMNAKDM4EL3MBTL1
SCHEMBL2931801 0.80 AKT1 (0.54) ALDH1A1LMNAKDM4EPTGS2EPHX1
SCHEMBL3491749 0.78 RAB9A (0.56) MAPTALDH1A1LMNAL3MBTL1SMN1; SMN2
SCHEMBL28959084 0.77 MAPT (0.61) MAPTALDH1A1LMNAKDM4EL3MBTL1
SCHEMBL4924405 0.76 ALDH1A1 (0.55) MAPTALDH1A1LMNAKDM4EL3MBTL1
SCHEMBL9343721 0.75 TGM2 (0.61) MAPTALDH1A1LMNAKDM4EL3MBTL1
SCHEMBL24554797 0.74 ALDH1A1 (0.53) MAPTALDH1A1LMNAKDM4EL3MBTL1
SCHEMBL13273458 0.74 ALDH1A1 (0.57) MAPTALDH1A1LMNAKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0907107-B1 Package of photosensitive planographic printing plates FUJI PHOTO FILM CO LTD (JP) 2003-04-02 EP disclosed
US-6534234-B1 Superposing a photosensitive planographic printing plate and a protection paper alternately to protect the surface of the photosensitive layer from abrasion FUJI PHOTO FILM CO., LTD. (JP) 2003-03-18 US disclosed
EP-0716347-B1 Developer for photosensitive lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2002-07-24 EP disclosed
EP-0730979-B1 Support for lithographic printing plate, process for the preparation thereof and electrochemical roughening apparatus FUJI PHOTO FILM CO LTD (JP) 2000-08-30 EP disclosed
US-6030748-A PHOTOSENSITIVE LAYER OF A HYDROLYZED AND POLYCONDENSED POLYMER OF ORGANOSILICONE OR ORGANOMETALLIC COMPOUND MONOMER IN A SOLVENT HAVING DISSOLVED THEREIN A PHENOL COMPOUND OR AN ORGANIC PHOSPHORIC ACID FUJI PHOTO FILM CO., LTD. (JP) 2000-02-29 US disclosed
EP-0907107-A2 Package of photosensitive planographic printing plates and photosensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1999-04-07 EP disclosed
US-5837345-A Support for lithographic printing plate, process for the preparation thereof and electrochemical roughening apparatus FUJI PHOTO FILM CO., LTD. (JP) 1998-11-17 US disclosed
US-5837425-A PRESENSITIZATION OF PLATES, SUPPORTS, MULTILAYER, EXPOSURE TO ACTINIC RADIATION OF FILMS, DEVELOPMENT OF PLATES WITH ALKALI FUJI PHOTO FILM CO., LTD. (JP) 1998-11-17 US disclosed
EP-0730979-A2 Support for lithographic printing plate, process for the preparation thereof and electrochemical roughening apparatus FUJI PHOTO FILM CO., LTD. (JP) 1996-09-11 EP disclosed
EP-0716347-A1 Developer for photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1996-06-12 EP disclosed