Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 7/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125038 | 0.83 | VCAM1 (0.60) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL29805549 | 0.83 | VCAM1 (0.60) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL11689602 | 0.80 | TSHR (0.50) | ALDH1A1MAPTCYP3A4HSD17B10VCAM1 | |
| SCHEMBL9793498 | 0.77 | PTPN11 (0.49) | ALDH1A1MAPTCYP3A4ALOX15VCAM1 | |
| SCHEMBL14714243 | 0.76 | MAPT (0.53) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL2372334 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MAPTVCAM1PTPN11P2RY6 | |
| SCHEMBL2683998 | 0.75 | VCAM1 (0.69) | VCAM1MAPK1TDP1 | |
| SCHEMBL11377708 | 0.75 | MAPK1 (0.56) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL2394881 | 0.75 | MAPT (0.58) | ALDH1A1MAPTCYP3A4ALOX15VCAM1 | |
| SCHEMBL10971487 | 0.74 | ALDH5A1 (0.65) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | HSD17B13, HSD17B3, HSD17B1 | ALDH1A1 98/4885MAPT 2885/4885KDM4E 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.