Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27570709 | 0.81 | NPC1 (0.47) | NPC1RAB9ACA2ALDH1A1MAPT | |
| SCHEMBL1130280 | 0.78 | MAPT (0.47) | CA2MAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL9075962 | 0.75 | MAPT (0.47) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29323796 | 0.74 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9555297 | 0.74 | KMT2A (0.48) | CA2ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL432741 | 0.74 | KMT2A (0.58) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8896484 | 0.74 | ALDH1A1 (0.50) | NPC1CA2ALDH1A1KMT2ALMNA | |
| SCHEMBL11878300 | 0.74 | ALDH1A1 (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL434364 | 0.72 | LMNA (0.57) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29323726 | 0.72 | ALDH1A1 (0.41) | CA2ALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240241440-A1 | POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2024-07-18 | — | — | US | disclosed |
| US-20240241440-A1 | POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2024-07-18 | — | — | US | disclosed |