SCHEMBL29324049

SCHEMBL29324049

CC(=O)c1cccc(NC(=O)CN2CCN(C(=O)OC(C)(C)C)CC2)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.47
CHRM4 P08173 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47
ALDH1A1 P00352 8/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ITGA4 P13612 1/20 0.46
ITGB7 P26010 1/20 0.46
RXFP1 Q9HBX9 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
MAPK10 P53779 1/20 0.44
LMNA P02545 1/20 0.43
TERT O14746 1/20 0.43
CYP2C19 P33261 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31254090 0.82 ITGA4 (0.48) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL18072532 0.78 CHRM3 (0.53) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL21685972 0.77 ALDH1A1 (0.78) ALDH1A1SMN1; SMN2GAAHPGDHSD17B10
SCHEMBL30014892 0.77 ALDH1A1 (0.78) ALDH1A1SMN1; SMN2GAAHPGDHSD17B10
SCHEMBL16577075 0.77 MEN1 (0.62) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL29324241 0.76 TGFBR1 (0.43) ALDH1A1RXFP1MEN1KMT2AKDM4E
SCHEMBL29210563 0.76 POLB (0.48) ALDH1A1SMN1; SMN2GAALMNAMAPT
SCHEMBL29324050 0.75 CHRM2 (0.47) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL23932570 0.75 TERT (0.46) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL30297583 0.75 TERT (0.46) CHRM2CHRM4CHRM1CHRM3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed