SCHEMBL29324241

SCHEMBL29324241

CC(=O)c1cccc(NC(=O)C(F)(F)C2CCN(C(=O)OC(C)(C)C)CC2)c1O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 4/20 0.43
PTPN2 P17706 1/20 0.43
PTPN1 P18031 1/20 0.43
PTPN6 P29350 1/20 0.43
KDM4E B2RXH2 1/20 0.42
PKM P14618 1/20 0.42
GPR119 Q8TDV5 6/20 0.41
STS P08842 1/20 0.41
MAPT P10636 1/20 0.40
NAMPT P43490 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 1/20 0.39
PDK1 Q15118 1/20 0.39
PDK2 Q15119 1/20 0.39
PDK3 Q15120 1/20 0.39
PDK4 Q16654 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324244 0.78 TGFBR1 (0.41) TGFBR1PTPN2PTPN1PTPN6KDM4E
SCHEMBL29324049 0.76 CHRM2 (0.47) KDM4EMAPTRXFP1MEN1KMT2A
SCHEMBL25003975 0.75 GPR119 (0.48) PTPN2PTPN1PTPN6KDM4EPKM
SCHEMBL29324248 0.73 SMN1; SMN2 (0.41) TGFBR1PTPN2PTPN1PTPN6KDM4E
SCHEMBL29324843 0.71 GPR119 (0.51) KDM4EPKMGPR119MAPTMEN1
SCHEMBL29324602 0.71 RXFP1 (0.52) KDM4ENAMPTRXFP1MEN1KMT2A
SCHEMBL29210563 0.71 POLB (0.48) GPR119MAPTNAMPTALDH1A1
SCHEMBL21752606 0.70 GPR119 (0.59) PTPN2PTPN1PTPN6KDM4EPKM
SCHEMBL25173198 0.69 HPGD (0.51) PTPN2PTPN1PTPN6KDM4EPKM
SCHEMBL23211982 0.67 MAPT (0.56) TGFBR1PTPN2PTPN1PTPN6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed