SCHEMBL29324050

SCHEMBL29324050

CC(C)(C)OC(=O)N1CCN(CC(=O)Nc2cccc3c(O)cc(=O)oc23)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.47
CHRM4 P08173 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47
CYP2C19 P33261 1/20 0.44
CETP P11597 1/20 0.44
BACE1 P56817 4/20 0.42
KDM1A O60341 2/20 0.41
TERT O14746 1/20 0.41
DTYMK P23919 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PARP1 P09874 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA5B Q9Y2D0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324244 0.80 TGFBR1 (0.41) BACE1KDM4E
SCHEMBL29324505 0.79 CHRM2 (0.43) CHRM2CHRM4CHRM1CHRM3KDM1A
SCHEMBL29324503 0.78 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3BACE1
SCHEMBL29324051 0.76 CHRM2 (0.46) CHRM2CHRM4CHRM1CHRM3CYP2C19
SCHEMBL29324049 0.75 CHRM2 (0.47) CHRM2CHRM4CHRM1CHRM3CYP2C19
SCHEMBL29324845 0.75 MAPK8 (0.45) KDM1AMEN1KMT2ACA12CA1
SCHEMBL29323211 0.74 ALDH1A1 (0.44) CHRM2CHRM4CHRM1CHRM3CETP
SCHEMBL31254090 0.73 ITGA4 (0.48) CHRM2CHRM4CHRM1CHRM3CYP2C19
SCHEMBL18072532 0.72 CHRM3 (0.53) CHRM2CHRM4CHRM1CHRM3CETP
SCHEMBL23932570 0.72 TERT (0.46) CHRM2CHRM4CHRM1CHRM3CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed