Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324423 | 0.74 | KMT2A (0.48) | ALDH1A1HPGDKDM4EHSD17B10CYP1A2 | |
| SCHEMBL11669157 | 0.70 | ALDH1A1 (0.75) | ALDH1A1HPGDKDM4EHSD17B10CYP1A2 | |
| SCHEMBL29324407 | 0.68 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EHSD17B10CYP1A2 | |
| SCHEMBL29324454 | 0.68 | KMT2A (0.41) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL30185626 | 0.67 | ALDH1A1 (0.81) | ALDH1A1HPGDKDM4EHSD17B10CYP1A2 | |
| SCHEMBL29324351 | 0.65 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EHSD17B10CYP1A2 | |
| SCHEMBL499644 | 0.65 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4EHSD17B10CYP1A2 | |
| SCHEMBL27794869 | 0.65 | ALDH1A1 (0.72) | ALDH1A1HPGDKDM4EHSD17B10CYP1A2 | |
| SCHEMBL7252159 | 0.64 | KDM4E (0.77) | ALDH1A1HPGDKDM4EHSD17B10CYP1A2 | |
| Oxolinic Acid SCHEMBL637058 | 0.64 | KDM4E (1.00) | ALDH1A1HPGDKDM4EHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151425-A1 | COMPOUNDS AND METHOD FOR TREATING HIV INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-07-18 | — | — | WO | disclosed |