Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324454 | 0.77 | KMT2A (0.41) | KMT2ALMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL29324427 | 0.74 | ALDH1A1 (0.47) | KMT2ALMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL29324341 | 0.72 | KDM4E (0.50) | KMT2ALMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL10612962 | 0.72 | HPGD (0.74) | KMT2ALMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL15282130 | 0.72 | KMT2A (0.73) | KMT2ALMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL9382762 | 0.72 | KMT2A (0.73) | KMT2ALMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL29324417 | 0.70 | GABRA1 (0.58) | KMT2AHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7128071 | 0.69 | KMT2A (0.76) | KMT2ALMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL11081172 | 0.68 | KDM4E (0.52) | LMNAHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4141591 | 0.68 | LMNA (0.61) | KMT2ALMNAHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151425-A1 | COMPOUNDS AND METHOD FOR TREATING HIV INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-07-18 | — | — | WO | disclosed |