Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 8/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330430 | 0.82 | PRKCQ (0.43) | SYKPRKCQMEN1KMT2ASIRT2 | |
| SCHEMBL29329292 | 0.82 | SIRT2 (0.41) | SYKPRKCQPRKCDMAPK1SIRT2 | |
| SCHEMBL29330342 | 0.82 | SYK (0.40) | SYKPRKCQRETPRKCDESR1 | |
| SCHEMBL29330343 | 0.80 | CHRNA7 (0.41) | SYKPRKCQPRKCDESR1SIRT2 | |
| SCHEMBL29328745 | 0.80 | PRKCQ (0.37) | SYKPRKCQRETPRKCDESR1 | |
| SCHEMBL29329866 | 0.80 | PRKCQ (0.38) | SYKPRKCQRETPRKCDMAPT | |
| SCHEMBL29330433 | 0.79 | SYK (0.41) | SYKPRKCQRETPRKCDESR1 | |
| SCHEMBL29328592 | 0.79 | SYK (0.45) | SYKPRKCQRETPRKCDESR1 | |
| SCHEMBL29329871 | 0.79 | RET (0.39) | SYKPRKCQRETPRKCDESR1 | |
| SCHEMBL29329528 | 0.79 | SYK (0.36) | SYKPRKCQRETPRKCDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |